Vaping vs. Smoking: What's the Nicotine Equivalent? Curious about how vaping compares to smoking? Let's break it down! Disposable Vapes: A typical disposable vape with around 600 puffs can The nicotine content of many 2ml nicotine pods for multi pod devices is equivalent to a pack of 20 cigarettes. If you don't smoke, don't vape. And if you are smoking Vapes vs Cigarettes: Which One is More Deadly? Atlus Which e cigarette is most like my favourite cigarette? : The Electric Tobacconist Ltd.