How Many Puffs of Vape is Equal to a Cigarette? UPENDS Vaping Student Health & Well Being One vape can equal 20 packs of cigarettes. That's how much nicotine some e cigarettes deliver fueling fast and dangerous addiction, especially among youth. Let's raise awareness and protect the next 1 electronic cigarette pod is roughly equal to 20 cigarettes' worth of nicotine, or 200 puffs. That's a lot! Make the choice not to let nicotine control your life. #EliminateTobacco and put