A regulatory haze: Vape marketers are online, creating new headaches for feds Salon.com Can Vaping Cause Headaches? Nicotine in vapes is highly addictive and can negatively impact a teen's developing brain, affecting memory, focus, and mood. Even short term use can cause headaches, nausea, sleep problems, and increased heart rate. Why Your THC Vape Pen Gives You a Headache
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