Hexose Monophosphate Pathway or Pentose Phosphate Pathway Animations PharmaXChange.info Pentose Phosphate Pathway Concise Medical Knowledge Glucose metabolism begins with its transport into cells via GLUT transporters, where it is phosphorylated to glucose 6 phosphate (Glucose 6 P). This molecule can enter various pathways, including the pentose phosphate pathway or hexosamine biosynthesis. Explain how Inactivity or absence of Glucose 6 phosphate dehydrogenase ; a rate limiting enzyme in the Pentose phosphate pathway could lead to oxidative stress.*