Losing weight with L carnitine supplements. Yes or no? Early research into L carnitine was often cited as underwhelming, showing negligible changes in muscle carnitine content and fat loss outcomes. However, these findings may have been limited by a short study window L Carnitine for weight loss is and heres why. There is zero published scientific data to support that L Carnitine actually helps you lose body fat. I went ahead and purchased the meta analysis The effect of (L)carnitine on weight loss in adults: a systematic review and metaanalysis of randomized controlled trials Pooyandjoo 2016 Obesity Reviews Wiley Online Library