Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione depletion biomarkers ophthalmic acid and 5 oxoproline in humans and rats Integrative Biology (RSC Acquired pyroglutamic acidosis due to long term dicloxacillin and paracetamol use BMJ Case Reports Pharmacology 401 k Paracetamol NAPQI Glutathione COX3 Poisoning Antidote AcetylCysteine Acetaminophen Pathway (toxic doses), Pharmacokinetics
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