Glutathione Benefits for Gut Health Nikki Yelton RD Glutathione Supplements: A Complete Guide Glutathione is a natural antioxidant your body makes, and it can influence melanin production which is why it's sometimes marketed for skin brightening. Oral supplements are mostly broken down in the University Did you know Glutathione is your body's master antioxidant? It protects your cells from damage, boosts energy levels, and supports your immune system, all while helping to detoxify your body.