High dose vitamin B12 supplements can sometimes cause side effects, including headache, nausea, vomiting, mild diarrhea, itching, skin rash, tiredness, weakness, or tingling in the hands and feet. OC: How Long Does a B12 Shot Last? LiveVibrant Wellness Guide Understanding the B12 Vitamin Shot: Benefits, Risks, and Dosage Guide B12 Injections and IV Infusion Treatments to Boost Your Vitality
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