Glutathione IV Therapy: What You Need to Know COEM Glutathione: Physiological and Clinical Relevance Restorative Medicine Glutathione is often called the body's master antioxidantand for good reason. It works at a cellular level to help protect against oxidative stress, support detoxification, and keep your system functioning efficiently. But Glutathione: your body's master antioxidant & detoxifier Glutathione is the 2nd most abundant molecule in the body, just after water. Its made from three amino acids: glycine, cysteine, & glutamate.