Safe intramuscular (IM) injection in the gluteal region is given in the upper outer quadrant to avoid sciatic nerve injury. Incorrect site selection (inner, lower, or medial areas) increases the risk of Buttock IM Injection Site: Master Safe 2025 Taylor demonstrates the proper technique for administering an intramuscular injection. Locate the upper, outer quadrant of the buttock muscle Prepare the site with alcohol Insert needle all the Buttock IM Injection Site: Master Safe 2025
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