Dietary allicin reduces transformation of L carnitine to TMAO through impact on gut microbiota ScienceDirect Could a mitochondrial metabolite known as acetyl L carnitine (LAC) yield a new biomarker for depression and potential new therapies? Dr. Carla Nasca, an @nyugrossman assistant professor of psychiatry and of neuroscience and physiology, Simultaneous quantification of trimethylamine oxide and its precursors from gut microbial metabolic pathway TMAO: The Gut Metabolite Linking Red Meat to Cardiovascular Disease