For CKD, I'd separate the proven support from the experimental but interesting category. Astragalus root extract is probably the most tried and true natural compound I'd look at first. There's actual human data showing Top 9 Benefits of NAC (N Acetyl Cysteine) Full article: Reduced glutathione ameliorates sepsis induced acute kidney injury in mouse model: involvement of cuproptosis Glutathione IV for Liver Detox: Support & Benefits AZ IV Medics
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glutathione or nac better APOL1 Renal Risk Variants and Sickle Cell Trait Associations With Reduced Kidney Function in a Large Congolese Population-Based Study