ECTOPIC trial: The efficacy of flEcainide Compared To metOprolol in reducing Premature ventrIcular Contractions: A randomized open label crossover study in pediatric patients Heart Rhythm Premature ventricular contractions (PVCs): Explained , PVCs are abnormal heartbeats that occur early on (prematurely) in the cardiac cycle. They originate in the ventricles (hence the name!) , Acetyl L Carnitine for Energy Support BioCeuticals Effect of Flecainide in Idiopathic Premature Ventricular Contractions and the Induced CardiomyopathyUNIFLECA: A Single Arm, Non Randomized Trial: Review of the Literature and Initial Results