Once weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double blind, placebo controlled and active controlled, dose finding phase 2 trial ScienceDirect Cagrilintide Side Effects, Complications, and Risk Profile Peptides.org When should I consider adding cagrilintide? Cagrilintide is the newest of the weight loss peptides. It works on amylin, which is found in the pancreas. Now, this can be a stand alone product but the Cagrilintide is an amylin analogue that helps regulate appetite. In a randomized trial of over 3400 patients who were overweight or obese and had 1 weight related complication, individuals assigned to a combination