FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology Molecular modelling of the FOXO4 TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells eBioMedicine Targeting the FOXO4 p53 axis by retro inverso peptide senolytic agents: a pharmacological strategy to mitigate brain aging and cognitive decline Naunyn Schmiedeberg's Archives of Pharmacology Springer Nature Link Frontiers FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway
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foxo4-dri senolytic human trial The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI