Tylenol Avoid or Not to Avoid? Acetaminophen (Tylenol) can deplete glutathione, your body's most important detox antioxidant. This matters even more if your child has an MTHFR gene mutation, which Please hear my heart here! There's no judgment from me, but this info is important and definitely not something widely talked about! It is very common advice parents receive to just give Frontiers Paracetamol Induced Glutathione Consumption: Is There a Link With Severe COVID 19 Illness? Oxidative stress mediates end organ damage in a novel model of acetaminophen toxicity in Drosophila Scientific Reports