Carcinoma associated fibroblast derived lysyl oxidase rich extracellular vesicles mediate collagen crosslinking and promote epithelial mesenchymal transition via p FAK p paxillin YAP signaling International Journal of Oral Science Introduction GHK Cu is a copper peptide complex formed from the tripeptide glycyl L histidyl L lysine bound to copper. This compound has garnered significant attention in both laboratory and formulation research due to its critical role GHK Cu Peptidos Glycation of type I collagen selectively targets the same helical domain lysine sites as lysyl oxidasemediated cross linking Journal of Biological Chemistry