Increasing glutathione levels by a novel posttranslational mechanism inhibits neuronal hyperexcitability ScienceDirect Frontiers Glutathione metabolism as a key regulator of oxidative hippocampal injury in sepsis associated encephalopathy: an integrated proteomics and metabolomics study Glycine and N acetylcysteine (NAC) are amino acidbased nutrients that serve as precursors for glutathione, one of the body's most important intracellular antioxidants. Glutathione plays a central role in reducing oxidative stress, supporting Frontiers Glutathione: A Samsonian life sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation