Frontiers Paracetamol Induced Glutathione Consumption: Is There a Link With Severe COVID 19 Illness? Since Tylenol is such a hot topic right now, did you know it depletes glutathione levels? When your body processes Tylenol in the liver, one of the pathways creates a toxic byproduct. To neutralize The gamma glutamyl pathway after glutathione depletion due to Download Scientific Diagram Deciphering Acetaminophen Induced Hepatotoxicity: The Crucial Role of Transcription Factors like Nuclear Factor Erythroid 2Related Factor 2 as Genetic Determinants of Susceptibility to Drug Induced Liver Injury Drug Metabolism and Disposition