Class 6 hmp pathway PPTX Biochemistry Lecture 37 Reactive Flashcards Cram Chronic Granulomatous Disease in Females: A Deficiency of Leukocyte Glutathione Peroxidase: New England Journal of Medicine: Vol 283, No 5 Full article: Glutathione metabolism rewiring protects renal tubule cells against cisplatin induced apoptosis and ferroptosis
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glutathione kidney function In G6PD deficiency (XR), we have increased oxidative damage to RBCs, leading to intravascular hemolysis with decreased serum haptoglobin. We have decreased NADPH production, which means decreased conversion of oxidized (-S-S-) glutathione