Glutathione Depletion and Stalwart Anticancer Activity of Metallotherapeutics Inducing Programmed Cell Death: Opening a New Window for Cancer Therapy ACS Omega Often, people take medications because they are deficient in certain nutrients, which can worsen their deficiencies. Instead, we can take the supplements in the first place. For example: If you're on Ask the Pharmacist: How glutathione is depleted from the body Role of Glutathione in Cancer: From Mechanisms to Therapies