L Carnitine: Benefits, Uses, Side Effects, and More Combining Berberine and L Carnitine can be beneficial for weight management, metabolism, and overall health. Berberine may improve insulin sensitivity, lower blood sugar, and support weight loss, while L carnitine helps the body use Dietary supplementation of l carnitine ameliorates metabolic syndrome independent of trimethylamine N oxide produced by gut microbes in high fat diet induced obese mice Food & Function (RSC Publishing) Muscle Specific Deletion of Carnitine Acetyltransferase Compromises Glucose Tolerance and Metabolic Flexibility ScienceDirect