Acetaminophen Use During Pregnancy and Autism Risk Acetaminophen can lower glutathione and use sulfate. V@ccine adjuvants like aluminum intentionally stimulate the immune system. Stacking these in sensitive windows can raise inflammatory load in Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome Scientific Reports