Glutathione System from Cyanobacteria to Higher Eukaryotes Encyclopedia MDPI General scheme of glutathione (GSH) conjugation to a generic Download Scientific Diagram GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY 16 Phase II reactions Conjugation with GSH paracetamol
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glutathione conjugation reaction Solved The stepwise mechanism below shows how glutathione