Does Glutathione Lighten Dark Spots? Glutathione and Vitamin C against hyperpigmentation Benefits of Glutathione for Skin 1. Brightens & evens skin tone Inhibits tyrosinase, the enzyme responsible for melanin production Helps reduce hyperpigmentation, melasma, and dark spots Promotes a more Glutathione is a powerful antioxidant that helps to brighten and even out skin tone, reduce inflammation, and protect against UV damage. It also plays a key role in detoxification and can help