Glutathione and Vitamin C: Your Skin's Brightening Duo Kabishah A Literature Review of Glutathione Therapy in Ameliorating Hepatic Dysfunction in Non Alcoholic Fatty Liver Disease Can you take glutathione without vitamin C? The simple answer: NO! Glutathione will not work without Vitamin C. Glutathione remains in two states, active and inactive. When it's in its active state, Glutathione: Benefits and Supplements