G6PD Deficiency causes Haemolytic Anaemia Glucose 6 phosphate dehydrogenase is an enzyme in the hexose monophosphate shunt that synthesizes NADPH. The NADPH is used to convert oxidized glutathione (GSSG) to reduced glutathione ( glucose pathways and G6PD Caspershire Meta Mini MCAT passage: Pentose phosphate pathway and G6DP deficiency (practice) Khan Academy Figure 2 from Impact of glucose 6 phosphate dehydrogenase deficiency on the pathophysiology of cardiovascular disease. Semantic Scholar