Glutathione Dependent Pathways in Cancer Cells Appraising the Role of Astrocytes as Suppliers of Neuronal Glutathione Precursors Glycine and N acetylcysteine (NAC) are amino acidbased nutrients that serve as precursors for glutathione, one of the body's most important intracellular antioxidants. Glutathione plays a central role in reducing oxidative stress, supporting Figure 3 from Glutathione synthesis. Semantic Scholar