Melanosis coli and colorectal cancer: Coincidence or correlated? ScienceDirect MELANOSIS COLI** Melanosis coli is a disorder of pigmentation of the bowel wall. Histology demonstrates pigment laden macrophages It is associated with laxative abuse, especially **anthraquinone compounds such as senna** Did you know that your child's poop is a window into their health? By paying attention to their bowel movements, you can get clues about whether your child is getting the nutrients Poop Patrol: Spotting Changes that Need Attention