Disturbing the Redox Balance Using Buthionine Sulfoximine Radiosensitized Somatostatin Receptor 2 Expressing Pre Clinical Models to Peptide Receptor Radionuclide Therapy with 177Lu DOTATATE Frontiers Glutathione Fine Tunes the Innate Immune Response toward Antiviral Pathways in a Macrophage Cell Line Independently of Its Antioxidant Properties 5 6) By contrast, latency I Burkitt B cells were particularly vulnerable to ferroptosis induction by blockade of either cystine import, glutathione synthesis or glutathione peroxidase 4 (GPX4). Eric also found roles for Glutathione depletion induces oxidative injury and apoptosis via TRPM2 channel activation in renal collecting duct cells ScienceDirect