The mechanism of action of N acetylcysteine (NAC): The emerging role of H2S and sulfane sulfur species ScienceDirect Glutathione is such an important antioxidant in human physiology, meaning it acts to combat oxidative stress. Strategies for increasing glutathione include: Consume sulfur rich foods like cruciferous vegetables Ensure you get N Acetyl Cysteine supplementation lowers high homocysteine plasma levels and increases Glutathione synthesis in the trans sulfuration pathway Italian Journal of Medicine A simultaneous liquid chromatography mass spectrometric assay of glutathione, cysteine, homocysteine and their disulfides in biological samples ScienceDirect