Nicotine Poisoning: What It Is, Symptoms, Causes & Treatment Latest Cochrane Review finds high certainty evidence that nicotine e cigarettes are more effective than traditional nicotine replacement therapy (NRT) in helping people quit smoking Cochrane E cigarettes helped 18,000 people quit smoking in 2015 but long term effects still unknown While vapes are less harmful than cigarettes, they shouldn't be used by those who don't smoke. Vaping and nicotine can have a harmful effect on the body, especially in children