Electronic cigarette use and its association with asthma, chronic obstructive pulmonary disease (COPD) and asthma COPD overlap syndrome among never cigarette smokers Frontiers Chronic obstructive pulmonary disease (COPD) and COPD like phenotypes A new study published in Nicotine & Tobacco Research found that those using e cigarettes alone were more than twice as likely to develop COPD than people who didn't use any tobacco products, The evolving epidemiology, disease trajectories and etiotypes of COPD ScienceDirect